Work flow of targeted prostate biopsy in 59 y.o. male with PSA 7.4 ng/ml, no palpable prostate lesion, and prior negative biopsy
A. T2-weighted axial MRI demonstrating a lesion in the left peripheral prostate.
B. Diffusion weighted MRI showing restricted diffusion (ADC value of 562) within the lesion.
C. Real-time ultrasound image of the lesion (outlined in blue) deriving from MRI fusion in Artemis device.
D and E. 3D reconstruction of prostate, based on ultrasound scan, showing lesion from MRI fusion (in blue) within the model, (D) saggital and (E) transverse views. Tan lines, which are image-captured biopsy sites, show sites of both systematic and targeted biopsy cores. Targeted biopsies in this patient revealed Gleason 7 prostate cancer.
F. Radical prostatectomy specimen showing tumor (dotted line) in whole mount section. Histologically, tumor was a 2 cm Gleason 7 cancer in the left peripheral zone.