A study to Compare Systematic vs. Targeted Biopsy (PairedCAP Study)
Technical Title: Phase II Clinical Trial to Determine Cancer Detection Rate of Systematic vs. Targeted Biopsy Methods in Diagnosis of Potentially Lethal Disease
Disease Type: Prostate cancer
This is a study for men with elevated PSA undergoing first-time biopsy. The purpose of the study is to evaluate the accuracy of a new biopsy technique which uses MRI guidance for targeted biopsy, compared to conventional blind biopsies that use only a transrectal ultrasound.
Research Procedures (not a complete list):
If you take part in the study, you will undergo a conventional ultrasound biopsy where 12 cores are collected. This will be followed by a targeted 3-core biopsy to the area that the radiologist designates as abnormal on the MRI, which means that the radiologist will be present during the biopsy to guide the urologist to the abnormal area. Another 3-core biopsy will follow, which will use fused ultrasound and MRI images to guide the biopsy location.
Eligibility Criteria (not a complete list):
For More Detailed Information, Contact: